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Only Available By Prescription
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zuplenz is a prescription antiemetic medication used to prevent nausea and vomiting resulting from chemotherapy, radiation treatments, or a surgery. Ondansetron is the active ingredient in Zuplenz and by blocking serotonin from the brain it means the nausea and vomiting response does not occur as pronouncedly following these treatments, or after a major surgery. You can buy Zuplenz from Canpharm.
| Fact Table | |
|---|---|
| Formula | C18H19N3O |
| License | FDA approved |
| Bioavailability | 56% (oral) |
| Legal status | Prescription Drugs |
| Chemical Name | 9-Methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one |
| Elimination half-life | 3-6 hours |
| Dosage (Strength) | 4mg, 8mg |
| Pregnancy | Consult Doctor |
| Brands | Zofran, Zuplenz |
| Protein binding | 70%-76% |
| PubChem CID | 4595 |
| MedlinePlus | a601209 |
| ChEBI | 7829 |
| ATC code | A04AA01 |
| DrugBank | DB00904 |
| KEGG | D00464 |
| Routes of administration | Oral, Buccal |
Follow dosage guidelines exactly as indicated in your prescription, and always take your medication only at the correct dosage strength
Remove a single film and place it on the top of your tongue
Allow dose to dissolve completely before swallowing it
If your indicated dosage is for more than one film, allow each film to dissolve completely before putting the next one in your mouth
Wash your hands after taking this medication
Zuplenz can be taken up to 3 times per day for 1 to 2 days and this will vary based on Ondansetron uses as needed and determined by your doctor
The active ingredient in Zuplenz is Ondansetron
Let your doctor know of any history of irregular heartbeat, liver dysfunction, or stomach / intestinal problems before starting on Zuplenz.
Use of this medication can be a cause QT prolongation, a heart condition that affects heart rhythm and can be a serious health risk for some people. Low levels of potassium may contribute to QT prolongation.
Only use medication during pregnancy or when breastfeeding if approved by a doctor.
Negative drug interactions may occur between Zuplenz and other Rx medications, including dofetilide, pimozide, procainamide, amiodarone, quinidine, sotalol, erythromycin, and several SSRi and SSNi antidepressants like Paxil, Prozac, Zoloft and others.
There are also significant toxicity risks if this medication is taken alongside street drugs like MDMA.
Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Zuplenz online.
Zuplenz side effects may occur, and some users may experience headache, light headedness, dizziness, tiredness, or constipation. If side effects are seen you may want to stop use and talk with a doctor again regarding other medications for nausea and vomiting relief after chemotherapy. For Zuplenz cost you can speak to a pharmacist.
What is Zuplenz, and what is it used for?
Zuplenz is an oral soluble film formulation of ondansetron, an antiemetic medication used primarily to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. Ondansetron works by blocking the actions of chemicals in the body that can trigger nausea and vomiting.
How do I take Zuplenz?
Zuplenz film is placed on the tongue, where it dissolves and can be swallowed without the need for water. Avoid handling the film excessively to ensure it dissolves effectively. Follow your doctor’s instructions closely regarding the timing and dosage, particularly if you are using it to prevent nausea related to specific treatments like chemotherapy.
What are the common side effects of Zuplenz?
Common side effects may include:
Most side effects are mild, but if you experience severe reactions, such as difficulty breathing, severe dizziness, or a fast or irregular heartbeat, seek medical help immediately.
Are there serious side effects to be aware of with Zuplenz?
Yes, some serious side effects include:
Who should not take Zuplenz?
Zuplenz is generally not recommended for individuals with a known allergy to ondansetron or similar medications. People with a history of QT prolongation, certain electrolyte imbalances, or heart rhythm disorders should consult their healthcare provider, as well as those with liver impairment or a history of phenylketonuria (PKU), as Zuplenz contains phenylalanine.
Can I take Zuplenz if I am pregnant or breastfeeding?
Zuplenz is generally used during pregnancy only if clearly needed, as ondansetron has been linked to a potential risk of fetal heart defects in some studies. If you are breastfeeding, consult your doctor, as ondansetron can pass into breast milk, though effects on nursing infants are not fully known.
Are there any drug interactions I should be aware of with Zuplenz?
Yes, Zuplenz can interact with:
Always inform your healthcare provider about all medications, supplements, and herbs you are taking.
What should I do if I miss a dose?
If you miss a dose of Zuplenz, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up. Follow your doctor’s instructions on adjusting the schedule if needed.
Can Zuplenz cause drowsiness?
Zuplenz is not typically associated with drowsiness. However, some people may feel dizzy or fatigued. Avoid driving or operating machinery until you know how it affects you.
How should I store Zuplenz?
Store Zuplenz at room temperature, away from moisture and heat. Keep it in its original packaging until use to protect it from light and moisture.
