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Xadago (Safinamide)

Also Known as Onstryv

Prescription requiredOnly Available By Prescription
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Description

Xadago is a medication formulated to target the underlying mechanisms of Parkinson's disease. As a selective and reversible monoamine oxidase type B (MAO-B) inhibitor, Xadago works by modulating dopamine levels in the brain. By inhibiting the breakdown of dopamine, Xadago helps maintain optimal dopamine levels, crucial for regulating movement and coordination.

The unique pharmacological profile of Xadago allows for its use as an adjunct therapy to levodopa/carbidopa in patients with PD experiencing off episodes, where symptoms re-emerge or worsen between medication doses. By extending the duration of symptom relief and reducing fluctuations in motor function, Xadago enables patients to regain control over their movements and enjoy a more predictable response to treatment.

Before you buy Xadago, it is crucial that you talk to your healthcare provider about potential side effects and Xadago cost.

Fact Table
Formula C17H19FN2O2
License FDA approved
Bioavailability 95%
Legal status Prescription drug
Chemical Name Safinamide
Elimination half-life 20-30 hours
Dosage (Strength) 50mg, 100mg
Pregnancy Consult doctor
Brands Xadago
Protein binding 88-90%
PubChem CID 6918314
MedlinePlus a617046
ChEBI CHEBI:90915
ATC code N04BD03
DrugBank DB06654
KEGG D09962
Routes of administration By mouth

Buy Xadago (Safinamide) online from online Canadian Pharmacy | CanPharm.com

Directions

Xadago is available in tablet form for oral administration. The recommended starting dose is 50 mg once daily, taken orally with or without food. Depending on individual response and tolerability, the dosage may be titrated upwards to a maximum of 100 mg once daily, as directed by a healthcare professional.

It is essential to adhere strictly to the prescribed dosage and administration schedule outlined by your healthcare provider. Do not exceed the recommended dose unless specifically instructed to do so by your doctor.

Ingredients

Xadago uses safinamide as its active ingredient.

Cautions

Individuals with a known hypersensitivity to safinamide or any components of the formulation should avoid using Xadago.

Xadago should be used with caution in patients with hepatic impairment, as safinamide metabolism may be altered in this population. Close monitoring is recommended.

Xadago may cause orthostatic hypotension or hypertension. Patients should be monitored for changes in blood pressure, particularly during the initial titration phase.

Psychiatric adverse reactions, including hallucinations and psychotic behavior, have been reported with Xadago use. Patients should be monitored for changes in mood or behavior and instructed to report any concerning symptoms promptly.

Interactions

Xadago has the potential to interact with a variety of medications, altering their efficacy or increasing the risk of adverse effects. It is essential to inform your healthcare provider of all prescription, over the counter, and herbal products you are taking before starting Xadago therapy. Some notable drug interactions include monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), dopamine agonists and ciprofloxacin.

Side Effects

While Xadago is generally well-tolerated, like all medications, it may cause side effects in some individuals. Common side effects associated with Xadago include:

  • Dyskinesia
  • Insomnia
  • Nausea
  • Headache
  • Orthostatic Hypotension

Frequently Asked Questions about Xadago (safinamide)


What is Xadago (safinamide)?

Xadago is a prescription medication used to treat Parkinson's disease.


How does Xadago work?

It works by increasing the levels of dopamine, a chemical in the brain that is important for movement.


Who should not take Xadago?

People with severe liver disease or who are taking certain medications should not take Xadago.


What are the common side effects of Xadago?

Common side effects include insomnia, dizziness, nausea, and falls.


Can Xadago be taken with other Parkinson's medications?

Yes, it can be used in combination with levodopa or other Parkinson's medications.


Are there any dietary restrictions while taking Xadago?

It's important to avoid foods high in tyramine, such as aged cheese and cured meats.


What should I do if I miss a dose of Xadago?

Take the missed dose as soon as you remember, unless it's almost time for your next dose.


Can Xadago cure Parkinson's disease?

No, there is no cure for Parkinson's disease, but Xadago can help manage symptoms.


How long does it take for Xadago to start working?

It may take a few weeks to notice an improvement in symptoms.


Is Xadago safe for long-term use?

Yes, Xadago is generally safe for long-term use when taken as directed by a doctor.