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Get my coupon now No thanks, I'd like to pay full priceAlso Known as Vastarel MR
Only Available By Prescription
Top brand choice
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Vastarel is a stable angina treatment medication that is used to reduce arterial pressure on the heart, and Vastarel uses may also be to prevent heart failure or for treatment of peripheral artery disease. Trimetazidine is an anti-ischemic metabolic agent that improves blood flow into the heart and the body’s ability to metabolize fatty acids. Patients on this medication will have less pain from angina and be less at risk of a cardiac event because of insufficient oxygenated blood flow into the heart. You can buy Vastarel MR with a prescription here at Canpharm.
| Fact Table | |
|---|---|
| Formula | C14H22N2O3 |
| License | Approved in various countries (not FDA-approved) |
| Bioavailability | ~90% |
| Legal status | Prescription Drug |
| Chemical Name | 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride |
| Elimination half-life | ~6 hours |
| Dosage (Strength) | 35mg modified-release tablets |
| Pregnancy | Consult Doctor (Not recommended in pregnancy) |
| Brands | Vastarel MR, Preductal MR, Trimetacor |
| Protein binding | ~16% |
| PubChem CID | 5734 |
| MedlinePlus | Not available |
| ChEBI | 45954 |
| ATC code | C01EB15 |
| DrugBank | DB08999 |
| KEGG | D07161 |
| Routes of administration | By mouth |
Standard dosage for Vastarel medication is to take 1 20mg or 35mg tablet 2x daily with food in the morning and evening
The active ingredient in Vastarel MR is Trimetazidine
Let your doctor know of any history of Parkinson's disease, renal impairment, hypertension (high blood pressure), or restless leg syndrome before starting on Vastarel
Women who are pregnant or breastfeeding should only use this medication if a doctor approves it
This medication is only approved for use with ages 18 and up
Be aware of medication expiry date
There are no established drug interaction risks between Vastarel MR and other Rx or OTC medications, but you should tell your doctor of all medications you are currently taking before getting and prescription and proceeding to buy Vastarel MR online.
Vastarel side effects may occur, and some users may experience weakness, dizziness, headache, stomach pain, diarrhea, indigestion, vomiting, rash, itching, or hives. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss angina treatment medication alternatives.
What is Vastarel MR used for?
Vastarel MR (trimetazidine) is used to treat stable angina pectoris (chest pain caused by reduced blood flow to the heart). It helps improve the heart's efficiency in using oxygen and reduces the frequency of angina attacks.
What is the mechanism of action of Vastarel?
Trimetazidine enhances cardiac cell metabolism by shifting energy production from fatty acid oxidation to glucose oxidation. This improves energy efficiency and reduces oxygen demand in the heart cells during ischemic episodes.
What are the positive effects of trimetazidine?
When do you stop taking Vastarel?
Stop taking Vastarel only if advised by your doctor. It may be discontinued if your symptoms are well-managed, if you experience side effects, or if it is no longer considered appropriate for your condition.
What happens if you stop taking trimetazidine?
Stopping trimetazidine may result in the recurrence or worsening of angina symptoms. Always consult your doctor before discontinuing the medication.
Does Vastarel affect blood pressure?
Vastarel does not directly affect blood pressure. It works by improving cardiac efficiency without causing significant changes in blood pressure or heart rate.
What to avoid when taking trimetazidine?
What does trimetazidine do to your heart?
Trimetazidine improves the heart's energy metabolism and reduces damage caused by ischemia (low oxygen supply). It helps the heart function more effectively without increasing its workload.
Should trimetazidine be taken at night or morning?
Trimetazidine can be taken in the morning or evening, depending on your doctor’s recommendation. It is usually taken twice daily, and consistency in timing is important.
Does trimetazidine affect the kidneys?
Trimetazidine may affect kidney function, particularly in individuals with preexisting kidney disease. Dosage adjustments may be required for patients with impaired renal function. Always monitor kidney health during treatment.
