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Trulance (Plecanatide)

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Trulance is an IBS-C treatment medication used for relief of chronic constipation. Plecanatide is a guanylate cyclase-C agonist drugs that promotes more fluid production in the bowel so that stool is softened and bowel movements occur more easily. Trulance also works to move food through the GI tract more quickly and this helps to reduce constipation too. You can buy Trulance with a prescription here at Canpharm.

Fact Table
Formula C65H104N18O26S4
License FDA approved
Bioavailability Negligible (acts locally in the gastrointestinal tract)
Legal status Prescription Drug
Chemical Name Plecanatide
Elimination half-life <1 hour (rapidly degraded in the GI tract)
Dosage (Strength) 3mg oral tablets
Pregnancy Consult Doctor (not recommended for use in pregnancy)
Brands Trulance
Protein binding Not applicable (acts locally in the GI tract)
PubChem CID 56843339
MedlinePlus a617019
ChEBI 134730
ATC code A06AX04
DrugBank DB12904
KEGG D10868
Routes of administration By mouth

Buy Trulance (Plecanatide) online from online Canadian Pharmacy | CanPharm.com

Directions

Take 1 3mg tablet once day with or without food as indicated in your prescription

Tablet may be crushed and mixed with water or applesauce

Crushed form of medication can be administered with a feeding tube

Ingredients

The active ingredient in Trulance is Plecanatide

Cautions

Let your doctor know of any history of chronic dehydration or gastrointestinal obstruction before starting on Trulance

Medication is only for use with ages 6 and up, and those under the age of 18 may not be suitable for taking Trulance

Be aware of medication expiry date

Medication is to be stored at room temperate and kept in a cool, dry place away from moisture

Keep out of reach of children and pets

Interactions

Negative drug interactions are possible between Trulance and other Rx medications, including idelalisib. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Trulance online.

Side Effects

Trulance side effects may occur, and some users may experience diarrhea, vomiting, nausea, or dehydration. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss IBS-C treatment medication alternatives and a pharmacist for a lower Trulance cost.

Frequently Asked Questions about Trulance (Plecanatide)


What is Trulance?

Trulance (plecanatide) is a prescription medication used to treat certain gastrointestinal conditions.


What is Trulance used for?

Trulance is used to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) in adults.


How does Trulance work?

Trulance works by stimulating the secretion of fluids in the intestines through activation of guanylate cyclase-C receptors. This helps soften stools and stimulate bowel movements.


How long does it take for Trulance to work?

Trulance can start working within 24–48 hours, but full effects may take a few days to a week, depending on the individual.


How long does Trulance stay in your system?

Trulance is minimally absorbed into the bloodstream and is mostly eliminated from the gastrointestinal tract within 24–48 hours.


How to take Trulance?

Take Trulance exactly as prescribed, usually once daily with or without food. Swallow the tablet whole, or if swallowing is difficult, it can be dissolved in water or mixed with applesauce.


Can I take Trulance twice a day?

No, Trulance is typically taken once daily. Taking it more frequently than prescribed can increase the risk of side effects like diarrhea.


Do Trulance side effects go away?

Most side effects, such as diarrhea, bloating, or gas, are mild and may resolve as your body adjusts to the medication. If side effects persist or worsen, consult your doctor.


Can I take Trulance at night?

Yes, Trulance can be taken at any time of the day, including at night. Consistency in timing may help maintain a regular bowel pattern.