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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Prezista (Darunavir) is a medication prescribed for the treatment of HIV-1 infection in adults. HIV-1 is the virus responsible for causing AIDS (Acquired Immune Deficiency Syndrome). To enhance the effectiveness of Prezista medication, it needs to be taken alongside specific medications like cobicistat and ritonavir, which help increase its levels in the body. However, it's important to note that darunavir does not provide a cure for HIV infection.
When considering treatment options for HIV-1 infection, it's important to consider factors such as effectiveness, potential side effects, and the Prezista cost.
HIV is a virus that attacks the immune system, while AIDS is the advanced stage of HIV infection. HIV weakens the immune system, making individuals more susceptible to infections and diseases. With proper medical care and treatment, people with HIV can live long and healthy lives without developing AIDS.
| Fact Table | |
|---|---|
| Formula | C27H37N3O7S |
| License | US DailyMed, EU EMA |
| Bioavailability | 37% |
| Legal status | Rx-Only |
| Chemical Name | Darunavir |
| Elimination half-life | 15 hours |
| Dosage (Strength) | 400mg, 600mg, 800mg |
| Pregnancy | Consult Doctor |
| Brands | Prezista |
| Protein binding | 95% |
| PubChem CID | 213039 |
| MedlinePlus | a607042 |
| ChEBI | 367163 |
| ATC code | J05AE10 |
| DrugBank | DB01264 |
| KEGG | D03656 |
| Routes of administration | By mouth |
Take darunavir dosage orally with food as instructed by your doctor.
Take once or twice a day, along with specific other medications at the same time every day.
Consult your doctor if you have difficulty swallowing tablets to inquire about using the liquid form.
Shake the bottle well before each dose if using the liquid form. Use a specialized measuring device to accurately measure the dose. Avoid using household spoons.
Do not exceed or reduce the prescribed dosage of darunavir or stop taking it without your doctor's approval, even for a brief period.
The active ingredient in Prezista is Darunavir.
Before using Prezista, disclose your medical history to your doctor, particularly if you have a history of liver problems, diabetes, hemophilia, lipid problems, or heart problems.
If you are pregnant, notify your doctor before using this medication. Treatment can reduce the risk of transmitting HIV infection to your baby.
The transfer of this medication into breast milk is not currently known or established. Since breast milk can transmit HIV, it is advised not to breastfeed while taking darunavir.
Prezista may have negative drug interactions with orlistat, carbamazepine, phenytoin, primidone, phenobarbital, secobarbital, elvitegravir, cobicistat, emtricitabine, tenofovir, alfuzosin, tamsulosin, midazolam, triazolam, bosutinib, dronedarone, dihydroergotamine, ergotamine, avanafil, sildenafil, lomitapide, pimozide, ranolazine, rivaroxaban, salmeterol, lovastatin, simvastatin, tolvaptan, apalutamide, garlic supplements, rifampin, rifapentine, St. John's Wort, among others.
Common side effects of Prezista include diarrhea, nausea, skin rash, headache, abdominal discomfort, and vomiting. There could be severe side effects of this medication. Before you buy Prezista and begin treatment, it is important to have a discussion with your doctor regarding the potential side effects and the effectiveness of the medication.
Can Prezista be crushed?
Prezista tablets should not be crushed or chewed and should be swallowed whole. Crushing or chewing them can affect their effectiveness.
What is the other name for Prezista?
The other name for Prezista is Darunavir.
What class of drug is Prezista?
Prezista belongs to the class of drugs known as protease inhibitors.
Who should not take Prezista?
Prezista should not be taken by individuals who are allergic to darunavir or any of the other ingredients in the medication. It is also not recommended for people with severe liver disease or those taking certain medications that may interact with Prezista.
