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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ongentys (opicapone) is a prescription medicine that inhibits the enzyme catechol-O-methyltransferase (COMT). COMT is involved in the degradation of certian neurotransmitters such as dopamine, epinephrine, and norepinephrine. Ongentys is used together with carbidopa and levodopa to treat symptoms of off episodes (stiffness, tremors, muscle spasms, poor muscle control) in people with Parkinson's disease. It is not known if Ongentys is safe and effective in children.
Take Ongentys exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. When you start or stop taking Ongentys, your doctor may need to adjust the doses of any other medicines you take for Parkinson's disease. Ongentys is usually taken at bedtime. Follow your doctor's dosing instructions very carefully. Take Ongentys on an empty stomach. Do not eat for at least 1 hour before or 1 hour after taking this medicine. Your blood pressure may need to be checked often. Ongentys may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. Do not change your doses or stop using any of your medicines without your doctor's advice. Tell your doctor if any of your medicines seem to stop working. Store at room temperature away from moisture and heat.
You should not use Ongentys if you are allergic to opicapone, or if you have a certain type of tumor that secretes hormones, such as: pheochromocytoma (tumor of the adrenal gland); or paraganglioma (tumor of the nerve cells). To make sure Ongentys is safe for you, tell your doctor if you have ever had: a sleep disorder that causes daytime sleepiness; narcolepsy or other conditions that cause sudden sleepiness; uncontrolled muscle movements; unusual and intense urges to act on impulse (such as gambling, binge-eating, or compulsive shopping); mental illness, hallucinations, or psychosis; liver disease; or kidney disease. Tell your doctor if you are pregnant or breastfeeding.
