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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Nizoral 2% is a medicated dandruff shampoo that eliminates scalp dandruff and can be used for seborrheic dermatitis treatment. The active ingredient in this OTC dandruff shampoo - Ketoconazole - works by preventing Malassezia fungus from forming proper cell walls so that fungal growth cannot continue and result in worsening dandruff. This means less flakes on the scalp and being visible in hair, and users with chronic dandruff can use Ketoconazole shampoo to prevent dandruff.
You can buy Nizoral without a prescription, and your best price on it will be when you order medication online from Canada and Canpharm.
Fact Table | |
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Formula | C26H28Cl2N4O4 |
License | FDA approved (OTC and prescription versions available) |
Bioavailability | Minimal systemic absorption when applied topically |
Legal status | Over-the-counter (OTC) and Prescription Drug (depending on country/strength) |
Chemical Name | cis-1-Acetyl-4-[4-[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine |
Elimination half-life | Not applicable (topical application results in negligible systemic absorption) |
Dosage (Strength) | 2% (20 mg/mL) shampoo |
Pregnancy | Consult Doctor (limited absorption via scalp; likely safe, but Category C due to lack of studies) |
Brands | Nizoral, Ketozal, Sebizole |
Protein binding | Not applicable for topical use |
PubChem CID | 3823 |
MedlinePlus | a682816 |
ChEBI | 48914 |
ATC code | D01AC08 |
DrugBank | DB01026 |
KEGG | D00351 |
Routes of administration | Topical (shampoo applied to scalp) |
Apply 5 to 10ml of Nizoral 2% dandruff shampoo to wet scalp and work into a lather.
Allow to remain for 3 - 5 minutes before rinsing with water.
For dandruff treatment: Apply 2x a week for 2 to 4 weeks.
For dandruff prevention: Apply 1x every 1 to 2 weeks.
The active ingredient in Nizoral shampoo is Ketoconazole.
For topical scalp use unless directed otherwise by your physician.
Keep out of eyes, ears, nose, and mouth.
Be mindful of expiry date for product when you buy Nizoral shampoo.
Side effects from using Nizoral 2% may occur, and some users may experience dry skin or dryness or oiliness of the hair and scalp. If side effects are seen you may want to stop use and speak to a pharmacist again regarding dandruff treatment options.
How to use Nizoral Anti-Dandruff Shampoo?
To use Nizoral Anti-Dandruff Shampoo, apply a small amount to wet hair, lather, and massage into the scalp. Leave the shampoo on for 3–5 minutes before rinsing thoroughly. Use it twice a week or as directed by your doctor for optimal results.
Does Nizoral Anti-Dandruff Shampoo work?
Yes, Nizoral Anti-Dandruff Shampoo is effective in treating dandruff. It contains ketoconazole, an antifungal agent that helps control the growth of the fungus Malassezia, which is often linked to dandruff.
Does Nizoral Anti-Dandruff Shampoo cause hair loss?
Hair loss is not a common side effect of Nizoral Anti-Dandruff Shampoo. In some cases, irritation from the shampoo or overuse may contribute to hair shedding, but this is generally not related to the active ingredient itself.
Is Nizoral Anti-Dandruff Shampoo safe?
Nizoral Anti-Dandruff Shampoo is generally considered safe for most people when used as directed. However, excessive use or sensitivity to the ingredients can lead to scalp irritation or dryness.
Is Nizoral Shampoo effective for dandruff?
Yes, Nizoral Shampoo is highly effective for treating dandruff caused by fungal infections like Malassezia. It helps reduce flakiness, itching, and irritation associated with dandruff.
How often should you use Nizoral Shampoo for dandruff?
For best results, use Nizoral Anti-Dandruff Shampoo twice a week. If your dandruff is severe, you may use it more frequently, but always follow the instructions on the product label or your doctor’s recommendations.
Can Nizoral Shampoo be used on color-treated hair?
Yes, Nizoral Shampoo can be used on color-treated hair, but it's best to use it as directed to prevent drying out the hair or scalp. If you have concerns, you can discuss with your dermatologist.
Can Nizoral Shampoo treat other scalp conditions?
Nizoral Shampoo is primarily used to treat dandruff, but it may also help with other fungal-related scalp conditions like seborrheic dermatitis or fungal infections of the scalp.
Can Nizoral Shampoo cause skin irritation?
While uncommon, some people may experience skin irritation or a burning sensation when using Nizoral Shampoo. If irritation occurs, reduce the frequency of use or discontinue and consult your doctor.
How long does it take for Nizoral to work for dandruff?
Most people start to see improvements within 2–4 weeks of using Nizoral Anti-Dandruff Shampoo regularly. If there’s no improvement after several weeks, consult a healthcare provider.