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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ngenla (Somatrogon) is a prescribed drug authorized for use in treating children who experience growth failure because they do not produce enough natural growth hormone (GH). Somatrogon is a long-acting recombinant human growth hormone (r-hGH) designed to mimic the natural pattern of growth hormone in the body. This once-weekly injectable therapy offers an alternative to daily growth hormone injections, providing convenience and potentially improving adherence to treatment.
Before you buy Ngenla pen, it is crucial that you talk to your healthcare provider about potential side effects and Ngenla cost.
| Fact Table | |
|---|---|
| Formula | C990H1528N262O300S7 (Somatrogon) |
| License | FDA approved |
| Bioavailability | High |
| Legal status | Prescription Drug |
| Chemical Name | Somatrogon |
| Elimination half-life | Approximately 28 hours |
| Dosage (Strength) | Available in different strengths |
| Pregnancy | Consult healthcare provider |
| Brands | Ngenla |
| Protein binding | High |
| PubChem CID | Not available |
| MedlinePlus | Not listed specifically for Ngenla |
| ChEBI | Not available |
| ATC code | H01AC07 |
| DrugBank | DB16698 (Somatrogon) |
| KEGG | D11742 (Somatrogon) |
| Routes of administration | Subcutaneous injection |
Ngenla should be administered once weekly via subcutaneous injection. The dosage depends on the weight of the patient and must be determined by a healthcare provider.
The active ingredient in Ngenla is somatrogon.
Before starting Ngenla Somatrogon, inform your healthcare provider about all medical conditions, especially if you have diabetes, thyroid problems, or a history of tumors.
Patients with active malignancy should avoid using somatrogon.
Regular monitoring of growth progress, hormone levels, and other health indicators is necessary during treatment.
Ngenla can interact with glucocorticoids, insulin and oral diabetes medications, other hormone therapies. Always discuss all medications and supplements you or your child are taking with your doctor to manage potential interactions.
Common side effects of Ngenla may include:
What is the drug NGENLA used for?
NGENLA (somatrogon) is a long-acting human growth hormone (hGH) analog used to treat pediatric patients who have growth failure due to inadequate secretion of endogenous growth hormone.
Is NGENLA approved by the FDA?
As of the latest update, NGENLA (somatrogon) has not been approved by the FDA. Approval status may change, so it's important to consult current FDA resources or your healthcare provider for the latest information.
How effective is NGENLA?
Clinical trials have shown NGENLA to be effective in increasing growth rates in children with growth hormone deficiency. It has demonstrated comparable efficacy to daily somatropin injections, with the advantage of a reduced injection frequency.
What are the contraindications for NGENLA?
NGENLA is contraindicated in patients with:
Is somatropin HGH?
Yes, somatropin is a form of human growth hormone (HGH) used to treat growth hormone deficiency and certain other conditions related to growth failure.
How to use NGENLA?
NGENLA is administered as a subcutaneous injection, typically once weekly. The injection should be given at the same time each week, and the site of injection should be rotated to reduce the risk of skin reactions.
What are the injection site reactions for NGENLA?
Common injection site reactions for NGENLA include:
These reactions are generally mild and resolve on their own.
How much somatropin should I take a day?
The dosage of somatropin varies depending on the individual's condition, age, and response to treatment. For pediatric growth hormone deficiency, the typical dosage is 0.16 to 0.24 mg/kg body weight per week, divided into daily injections. Always follow your healthcare provider's specific dosage instructions.
What is the risk of somatropin?
The risks of somatropin include:
Discuss potential risks with your healthcare provider.
Can you drink alcohol while taking somatropin?
It is generally advisable to limit alcohol consumption while taking somatropin, as alcohol can interfere with the effectiveness of the medication and exacerbate side effects.
What happens if you take too much somatropin?
Overdosing on somatropin can lead to symptoms such as:
In severe cases, it can cause serious complications such as acromegaly (abnormal growth of hands, feet, and facial features) and organ enlargement. Seek immediate medical attention if an overdose is suspected.
How long does it take for somatropin to work?
The effects of somatropin can vary, but improvements in growth rates in children are typically observed within 3 to 6 months of starting treatment. Full therapeutic effects can take longer, and regular monitoring by a healthcare provider is necessary to assess progress and adjust dosages as needed.
