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Mirapex ER (Pramipexole ER)

Also Known as Mirapexin P/R

Prescription requiredOnly Available By Prescription
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Description

Mirapex is a prescription Parkinson's disease treatment medication that is used to improve movement and reduce tremors, stiffness, and unsteadiness for people with Parkinson's. In rarer instances it may also be prescribed as a treatment for restless legs syndrome. The active ingredient in this medication – Pramipexole – is a dopamine agonist that increases dopamine levels in the brain by limiting the reuptake of the neurotransmitter so that more of it is present and active at all times. You can buy Mirapex ER at Canpharm.

What is Parkinson's Disease?

Parkinson's is a degenerative brain disease that causes the person to lose voluntary control of body movement and motor skills. This occurs when cells in the substantia negra part of the brain's basal ganglia start to die in large numbers. The basal ganglia is then unable to produce the neurotransmitter dopamine to the extent it needs to for normal control of body movement. It is quite common for symptoms of Parkinson's disease to not start being experienced until more than 70% of these cells have died.

Fact Table
Formula C10H17N3S
License FDA approved
Bioavailability >90%
Legal status Prescription Drugs
Chemical Name (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride
Elimination half-life 8-12 hours
Dosage (Strength) 0.375mg, 0.75mg, 1.5mg, 3mg, 4.5mg
Pregnancy Consult Doctor
Brands Mirapex, Mirapex ER
Protein binding ~15%
PubChem CID 119570
MedlinePlus a697029
ChEBI 8365
ATC code N04BC05
DrugBank DB00413
KEGG D01108
Routes of administration Oral

Buy Mirapex ER (Pramipexole ER) online from online Canadian Pharmacy | CanPharm.com

Directions

Standard dosage for Mirapex ER is to take one tablet 1x daily with water at the same time every day. Your dosage strength and number of tablets per day will vary based on your response to treatment and the severity of your Parkinson’s symptoms, and you should always take your medication exactly as indicated in your prescription.

Ingredients

The active ingredient in Mirapex ER is Pramipexole.

Cautions

Let your doctor know of any history of low blood pressure, heart problems, kidney failure or dysfunction, mental / mood or sleep disorders before starting on Mirapex ER.

Medication use may make you drowsy or dizzy, and it may be best to avoid driving or using machinery will you are taking Mirapex ER generic

Women who are pregnant or are planning to become pregnant should discuss using Mirapex ER before starting on the medication, and should only do so with the doctor's approval

Interactions

Negative drug interactions may occur between Mirapex ER and other Rx medications, including chlorpromazine, haloperidol, thiothixene, cimetidine, metoclopramide, cetirizine, diphenhydramine, alprazolam, diazepam, zolpidem, carisoprodol, cyclobenzaprine, codeine, and hydrocodone. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Mirapex ER online.

Side Effects

Mirapex side effects may occur, and some users may have nausea, dizziness, drowsiness, lightheadedness, trouble sleeping, constipation, headache, or dry mouth. If side effects are seen you may want to stop use and talk to a doctor again regarding Parkinson's disease treatment medication alternatives, and for Mirapex ER cost you can speak to a pharmacist.

Frequently Asked Questions about Mirapex ER (Pramipexole ER)


What is Mirapex ER (Pramipexole ER), and what is it used for?

Mirapex ER is an extended-release formulation of pramipexole, a dopamine agonist medication primarily used to treat Parkinson's disease symptoms. It helps manage motor symptoms like tremors, stiffness, and slow movement. Mirapex ER is also sometimes prescribed for restless legs syndrome (RLS), although this use is more common with the immediate-release form.


How does Mirapex ER work?

Mirapex ER works by stimulating dopamine receptors in the brain. Dopamine is a neurotransmitter involved in movement control, and its deficiency is linked to Parkinson's disease symptoms. By mimicking dopamine’s effects, pramipexole helps improve motor function and reduce symptoms.


How should I take Mirapex ER?

Take Mirapex ER once daily, usually at the same time each day. Swallow the tablet whole; do not crush, chew, or split it, as this may interfere with its extended-release mechanism. Follow your healthcare provider’s dosage instructions closely, and avoid sudden dose changes without medical guidance.


What are the possible side effects of Mirapex ER?

Common side effects include:

  • Nausea
  • Dizziness
  • Drowsiness
  • Constipation
  • Insomnia

Serious side effects may include hallucinations, sudden sleep episodes, compulsive behaviors (like gambling or eating), and orthostatic hypotension (dizziness when standing up). Contact your doctor if you experience any severe or unusual symptoms.


Are there any serious risks associated with Mirapex ER?

Yes, Mirapex ER may cause sudden drowsiness or sleep episodes, which can be dangerous if you're driving or operating machinery. It may also increase the risk of compulsive behaviors. Discuss these risks with your doctor, especially if you have a history of similar behaviors.


Can I drink alcohol while taking Mirapex ER?

It is generally advised to limit or avoid alcohol while taking Mirapex ER, as alcohol can increase side effects like drowsiness, dizziness, and risk of falls.


Are there any medications or substances I should avoid while taking Mirapex ER?

Certain medications may interact with Mirapex ER, including antipsychotics, sedatives, and other drugs that affect dopamine. Inform your healthcare provider about all medications, supplements, and over-the-counter products you use to avoid potential interactions.


How long does it take for Mirapex ER to start working?

Some symptom relief may be noticed within a few days, but it may take several weeks for full effects to become evident. Your healthcare provider may gradually increase your dose to reach the therapeutic level.


What should I do if I miss a dose of Mirapex ER?

If you miss a dose, take it as soon as you remember. However, if it’s near the time of your next dose, skip the missed dose. Do not double up on doses, as this could increase the risk of side effects.


Can I stop taking Mirapex ER suddenly?

No, you should not stop taking Mirapex ER abruptly, as it may cause withdrawal symptoms or worsen Parkinson’s symptoms. Consult your healthcare provider to taper off the medication safely if needed.