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Only Available By Prescription
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Migranal nasal spray is a migraine treatment medication that is administered as a mist that goes directly into the sinus for fast-acting migraine relief. It can be used by both people with standard migraines or those who get them with aura. Dihydroergotamine is an ergot alkaloid drug that targets serotonin receptors in the brain and the shrinking of blood vessels that results from it reduces the severity of migraine headaches and makes them less painful. You can buy Migranal nasal spray with a prescription here at Canpharm.
| Fact Table | |
|---|---|
| Formula | C33H37N5O5 |
| License | FDA approved |
| Bioavailability | ~32% (nasal spray) |
| Legal status | Prescription Drug |
| Chemical Name | (6aR,9R,10aR)-N-[(Hydroxyacetyl)-1-methylpropyl]-6a,10a-dihydro-12'-hydroxy-2',5',9-trimethyl-ergotaman-3',6',18-trione |
| Elimination half-life | ~10 hours |
| Dosage (Strength) | 4mg/mL solution (1mg per spray) |
| Pregnancy | Contraindicated (Category X) |
| Brands | Migranal |
| Protein binding | ~93% |
| PubChem CID | 441260 |
| MedlinePlus | a604028 |
| ChEBI | 4652 |
| ATC code | N02CA01 |
| DrugBank | DB00320 |
| KEGG | D07876 |
| Routes of administration | Intranasal |
Standard Migranal nasal spray dosage is to administer 1 dose of the spray as needed at the onset of a migraine headache
Administration:
The active ingredient in Migranal nasal spray in Dihydroergotamine
This medication is for nasal injection only and it should not be ingested in any other way
Do not give yourself more than 3 inhalations in a 24-hour period
Let your doctor know of any history of liver or kidney problems, poor heart health, high cholesterol, diabetes, peripheral vascular disease, Raynaud's syndrome, or hemiplegic or basilar headaches before starting with Migranal nasal spray
Woman who are pregnant should not use this medication because the risk of preterm labor and women who are breastfeeding should refrain from it for 3 days after administering a dose of this migraine nasal spray
Store at room temperature and away from moisture, heat, and light
Be aware of medication expiry date
Negative drugs interactions may occur between Migranal nasal spray and other Rx or OTC medications, including duloxetine, venlafaxine, cyclobenzaprine, sumatriptan, rizatriptan, eletriptan, montelukast, and ondansetron. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Migranal nasal spray online.
Migranal side effects may occur, and some users may experience runny or stuffy nose, nausea, vomiting, diarrhea, taste changes, localized irritation, dizziness, drowsiness, or sore throat. If side effects are seen you may want to meet a doctor to discuss migraine headache emergency relief medication alternatives and a pharmacist for a lower Migranal nasal spray price.
What is Migranal Nasal Spray used for?
Migranal Nasal Spray (dihydroergotamine) is used to treat acute migraine headaches with or without aura.
How does Migranal Nasal Spray work?
Migranal works by constricting blood vessels in the brain and reducing inflammation, which helps alleviate migraine pain and symptoms.
How should Migranal Nasal Spray be used?
Migranal Nasal Spray is typically sprayed into one nostril at the onset of a migraine. If needed, a second dose can be taken after 1 hour, as directed by your doctor.
What are the side effects of Migranal Nasal Spray?
Common side effects include nasal irritation, dizziness, nausea, and a sensation of tightness in the chest. Serious side effects may include high blood pressure, heart issues, or severe allergic reactions.
How long does it take for Migranal Nasal Spray to work?
Migranal typically starts working within 15 to 30 minutes to relieve migraine pain, although complete relief may take up to 2 hours.
Who should not use Migranal Nasal Spray?
Migranal should not be used by individuals with a history of heart disease, high blood pressure, or peripheral vascular disease, or those who are pregnant.
Can Migranal Nasal Spray interact with other medications?
Yes, Migranal can interact with other medications, especially other migraine treatments, triptans, or ergot-related medications. Inform your doctor of all other medications you are taking.
Can Migranal Nasal Spray cause rebound headaches?
Yes, frequent use of Migranal may lead to medication overuse headaches, where migraines worsen or become more frequent.
How should Migranal Nasal Spray be stored?
Store Migranal Nasal Spray at room temperature, away from heat and moisture, and keep the bottle tightly closed.
Can I stop using Migranal Nasal Spray suddenly?
Migranal Nasal Spray is used as needed for acute migraines, so there is no need to stop it suddenly. However, it should be used only as prescribed to avoid overuse and complications.
