A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Leucovorin is a form of folic acid. Folic acid helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer. Folic acid is present in many foods such as dried beans, peas, oranges, spinach, and others. Leucovorin is used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body. This includes methotrexate (Rheumatrex), pyrimethamine (Daraprim), trimethoprim (Trimpex, Proloprim), and others. Leucovorin may also be used for purposes not listed in this medication guide.
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. When treating an accidental overdose, leucovorin should be started as soon as possible for the best effect. Leucovorin is usually given with other medications to help your kidneys remove methotrexate from your body. You may also be treated with IV fluids to keep you from getting dehydrated. You will need frequent medical tests to help your doctor determine how long to treat you with leucovorin. Store at room temperature away from moisture, heat, and light.
The active ingredient in Leucovorin is leucovorin.
You should not take leucovorin if you have pernicious anemia or other types of anemia caused by a lack of vitamin B12.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.