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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Lagevrio, with its active ingredient molnupiravir, is an antiviral medication designed for the treatment of mild to moderate COVID-19 in adults. It is specifically intended for use in patients who are at risk of developing severe illness, including hospitalization or death, and for whom alternative COVID-19 treatment options authorized by the FDA are not accessible or clinically appropriate. Lagevrio works by introducing errors into the SARS-CoV-2 virus's RNA, curbing its ability to replicate within the body. This medication is provided in the form of capsules and is approved under Emergency Use Authorization by the FDA.
Before you buy Lagevrio, it is crucial that you talk to your healthcare provider about potential side effects and Lagevrio cost.
| Fact Table | |
|---|---|
| Formula | C13H21N3O7 |
| License | FDA Emergency Use Authorization (EUA) |
| Bioavailability | Approximately 88% |
| Legal status | Prescription-only (Rx) |
| Chemical Name | (2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl (2R,3S,4R)-3,4-Dihydroxy-5-oxopyrrolidin-2-yl]amino]acetate |
| Elimination half-life | Approximately 3.3 hours |
| Dosage (Strength) | 200 mg and 400 mg capsules |
| Pregnancy | Contraindicated due to potential teratogenicity |
| Brands | Lagevrio |
| Protein binding | Less than 50% |
| PubChem CID | 145996610 |
| MedlinePlus | a621009 |
| ChEBI | 155900 (Molnupiravir) |
| ATC code | J05AX30 |
| DrugBank | DB15661 (Molnupiravir) |
| KEGG | D11799 (Molnupiravir) |
| Routes of administration | Oral |
Lagevrio should be administered as soon as possible after a diagnosis of COVID-19 and within five days of symptom onset. The standard dosage is as follows:
Adults (18 years and older): Take 800 mg (four 200 mg capsules) every 12 hours for five days. Take the capsules whole with water, and you may take them either with or without food.
Do not discontinue the medication prematurely, even if symptoms resolve early. Completing the full course ensures the maximum effectiveness of the treatment.
Active ingredient: 200 mg molnupiravir.
Do not take Lagevrio if you have a known allergy to molnupiravir or any other component of the capsule.
There is evidence suggesting that molnupiravir may cause fetal harm when administered to pregnant women.
It is not known if molnupiravir or its metabolites are present in human breast milk. Consider the benefits of breastfeeding and the potential risk to the infant when making the decision to administer the drug while breastfeeding.
Safety and effectiveness in patients under 18 years of age have not been determined.
Patients with severe renal impairment or moderate to severe hepatic impairment should use this medication with caution and under close medical supervision.
Lagevrio 200 mg should be used cautiously with other medications due to potential interactions:
Antiviral agents: Concurrent use with other antiviral drugs that use similar mechanisms of action may increase the risk of adverse effects.
Vaccine efficacy: Lagevrio may reduce the efficacy of live or live-attenuated vaccines. Discuss with your healthcare provider the appropriate timing between taking Lagevrio and receiving vaccines.
Like all medications, Lagevrio can cause side effects, although not everyone experiences them. Common side effects include:
What exactly does Lagevrio do?
Lagevrio (molnupiravir) is an oral antiviral drug used to treat COVID-19. It works by stopping the coronavirus from replicating in the body, reducing the viral load and the chances of the illness progressing to more serious symptoms and hospitalization.
What are the common side effects of Lagevrio?
The most common side effects of Lagevrio are diarrhea, nausea, and dizziness.
What medications cannot be taken with Lagevrio?
Currently, there are no known drug interactions with Lagevrio.
How does Lagevrio make you feel?
Common side effects of Lagevrio include diarrhea, nausea, and dizziness. If these effects last or get worse, it’s recommended to tell your healthcare professional promptly.
Is Lagevrio safe to take?
Lagevrio has been authorized for emergency use by the FDA for the treatment of mild-to-moderate COVID-19 in adults who are at high risk for progression to severe COVID-19. However, all potential risks are not yet known as the drug is still being studied.
When is Lagevrio recommended?
Lagevrio is recommended for adults 18 years and older who have had mild to moderate COVID-19 symptoms for no more than 5 days and are not hospitalized. It is also recommended for those at high risk for COVID-19 complications due to older age, obesity, or ongoing medical conditions.
How long does it take for Lagevrio to work?
Lagevrio works best if started as soon as possible after a diagnosis of COVID-19, ideally within five days of first noticing signs of sickness.
How to take Lagevrio?
Lagevrio is taken orally every 12 hours (for example, at 8 am and at 8 pm) for 5 consecutive days. The capsules should be swallowed whole.
Can you drink alcohol while taking Lagevrio?
It’s not known if alcohol affects Lagevrio. However, if Lagevrio gives you headaches or makes you feel dizzy it’s best not to drink alcohol.
How long does Lagevrio stay in your system?
In non-pregnant adults, it takes up to 1 day, on average, for most of the Lagevrio to be gone from the body.
