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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Inclunox, with its active ingredient Enoxaparin, is a low molecular weight heparin (LMWH) primarily used in the prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). This anticoagulant medication is effective in reducing the ability of blood to clot. Enoxaparin is also employed in the management of acute coronary syndrome, including unstable angina and non-Q-wave myocardial infarction. Packaged as a pre-filled syringe, Inclunox is administered subcutaneously to ensure a steady absorption and consistent therapeutic levels.
Before you buy Inclunox, it is crucial that you talk to your healthcare provider about potential side effects and Enoxaparin price.
Fact Table | |
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Formula | C26H40N2O36S5 (average molecular structure) |
License | FDA approved |
Bioavailability | Subcutaneous: ~92% |
Legal status | Prescription Drugs |
Chemical Name | Enoxaparin sodium |
Elimination half-life | 4.5 hours (subcutaneous) |
Dosage (Strength) | Various, ranging from 30 mg to 150 mg prefilled syringes |
Pregnancy | Consult a healthcare provider |
Brands | Inclunox, Lovenox |
Protein binding | Low (<10%) |
PubChem CID | 108622 (for enoxaparin sodium) |
MedlinePlus | a601210 |
ChEBI | 63598 (Enoxaparin sodium) |
ATC code | B01AB05 |
DrugBank | DB01225 (Enoxaparin sodium) |
KEGG | D07941 (Enoxaparin sodium) |
Routes of administration | Subcutaneous |
Inclunox is intended for subcutaneous injection and should not be administered intramuscularly due to the risk of hematoma formation. Patients or caregivers should be trained by healthcare professionals on the proper technique to ensure safe administration. Take Enoxaparin dose exactly as prescribed by your healthcare provider. Continue to take Inclunox even if you feel well, unless advised otherwise by your doctor.
The active ingredient in Inclunox is Enoxaparin sodium.
Inclunox should be used with caution in patients with known hypersensitivity to heparin or pork products, as Enoxaparin is derived from porcine intestinal mucosa. Patients with active major bleeding, thrombocytopenia, or those who are undergoing spinal anesthesia or lumbar puncture should avoid using this medication due to the increased risk of spinal or epidural hematoma, which can lead to long-term or permanent paralysis.
Renal impairment significantly affects the clearance of Enoxaparin, and dose adjustments may be necessary to prevent bleeding complications. Regular monitoring of kidney function and platelet counts is advised.
Enoxaparin can interact with various drugs, increasing the risk of bleeding especially when used with antiplatelet agents (e.g., aspirin, clopidogrel), nonsteroidal anti-inflammatory drugs (NSAIDs) and other anticoagulants (e.g., warfarin, dabigatran). Consultation with a healthcare provider is essential before starting any new medications, including over-the-counter drugs and herbal supplements, to ensure they do not interact with Inclunox.
Common side effects of Inclunox include:
What is Inclunox?
Inclunox is a brand of enoxaparin, which is a type of anticoagulant medication. It is used to prevent and treat blood clots in the veins, including deep vein thrombosis (DVT) and pulmonary embolism (PE). It is also used to prevent complications in patients with certain types of heart conditions, such as unstable angina or non-Q-wave myocardial infarction.
How does Inclunox work?
Inclunox works by inhibiting certain proteins in the blood that are responsible for blood clotting. It enhances the activity of antithrombin III, which in turn inhibits the activity of factor Xa and thrombin, key components in the coagulation process. This helps prevent the formation of harmful clots in the blood vessels.
How is Inclunox administered?
Inclunox is typically administered as an injection under the skin (subcutaneously). It is often given in the abdomen area but can also be injected into other areas with a layer of fat, such as the thigh. The exact dosage and frequency depend on the medical condition being treated and the patient's specific circumstances.
What are the common side effects of Inclunox?
Common side effects of Inclunox include mild pain, redness, or irritation at the injection site. Some patients may also experience bleeding or bruising more easily, nosebleeds, and bleeding gums. If you notice any severe or unusual side effects, you should contact your healthcare provider immediately.
Who should not use Inclunox?
Inclunox should not be used by individuals with known hypersensitivity to enoxaparin or heparin, those with active major bleeding, or those with conditions such as heparin-induced thrombocytopenia (HIT). It is also contraindicated in patients with certain medical conditions that increase the risk of bleeding.
Can Inclunox be used during pregnancy?
Inclunox is sometimes used during pregnancy to prevent and treat blood clots, as it does not cross the placenta and is considered safer than some other anticoagulants. However, its use should be closely monitored by a healthcare provider to ensure the safety of both the mother and the developing baby.
What should I do if I miss a dose of Inclunox?
If you miss a dose of Inclunox, you should take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one. Consult your healthcare provider if you have any concerns.
Are there any dietary restrictions while using Inclunox?
While using Inclunox, it is generally advised to maintain a consistent diet. However, you should avoid excessive consumption of foods rich in vitamin K (such as leafy green vegetables) as they can interfere with anticoagulation. Always discuss any dietary changes with your healthcare provider.
Can Inclunox interact with other medications?
Yes, Inclunox can interact with other medications, including other anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain supplements. These interactions can increase the risk of bleeding. It is important to inform your healthcare provider about all medications and supplements you are taking.
How should Inclunox be stored?
Inclunox should be stored at room temperature, away from direct light and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the solution is discolored or contains particles. Dispose of it properly according to the guidelines provided by your healthcare provider or pharmacist.