Also Known as Puregon
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Gonal F (follitropin alfa) is a recombinant follicle stimulating hormone (rFSH) injection commonly used in assisted reproductive technologies like IVF (in vitro fertilization). It contains a hormone similar to the one produced by the human body, which helps stimulate the ovaries to produce eggs in women and sperm production in men. Gonal F is used to treat infertility in women, particularly those who have not responded to simpler treatments, and can also help men who have a hormonal imbalance that affects sperm production. This medication is available in pre-filled pens for easier dosing and administration.
Before you buy Gonal F pen, it is crucial that you talk to your healthcare provider about potential side effects and Gonal F cost.
Fact Table | |
---|---|
Formula | C975H1513N267O304S26 |
License | FDA approved |
Bioavailability | Not applicable (administered via injection) |
Legal status | Prescription Drugs |
Chemical Name | Recombinant Human Follicle Stimulating Hormone (r-hFSH) |
Elimination half-life | 44 hours (range 30-50 hours) |
Dosage (Strength) | Available in 300 IU, 450 IU, and 900 IU prefilled pens |
Pregnancy | Use only if clearly needed and potential benefits outweigh the risks |
Brands | Gonal-f |
Protein binding | Not applicable |
PubChem CID | 16132418 |
MedlinePlus | N/A |
ChEBI | 8272 |
ATC code | G03GA05 |
DrugBank | DB00066 |
KEGG | D02867 |
Routes of administration | Subcutaneous injection |
Preparation and Administration:
Wash your hands thoroughly before use.
Check the liquid in the pre-filled pen. It should be clear and colorless and never use if it is cloudy or contains particles.
Use the alcohol swab to clean the injection site (usually lower abdominal area or thigh).
Attach the needle securely to the pen, remove the cap, and check the flow by expelling a small amount of the solution.
Administer subcutaneously as directed by your healthcare provider.
Dispose of the needle in a proper sharps container.
Dosage:
The Gonal F dosage varies depending on individual patient needs, the type of treatment being administered, and specific recommendations from the healthcare provider.
Follow the dosage prescribed strictly without any alteration unless advised by your doctor.
Follitropin alfa is the active ingredient in Gonal F.
Gonal F should not be used by individuals who are allergic to follitropin alfa or any of its ingredients.
It should not be used by pregnant women, as it can cause harm to the fetus.
Women with primary ovarian failure should not use Gonal F, as it is unlikely to be effective.
Patients with uncontrolled thyroid, adrenal dysfunction, or pituitary tumors should avoid using this medication until adequate control of their conditions has been achieved.
Gonal F can interact with other fertility treatments and medications, potentially altering their effects. Always let your healthcare provider know about any other medications you are currently taking. Herbal supplements and over-the-counter drugs should also be discussed with a healthcare provider to avoid potential interactions.
Common side effects of Gonal F include:
What should I do if I miss a dose of Gonal F?
If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to make up for the missed one.
Can Gonal F increase the chance of having twins or multiples?
Yes, Gonal F can increase the likelihood of multiples (twins, triplets, etc.), as it stimulates the production of multiple eggs.
Is Gonal F used in men and women?
Yes, it is used in both men and women but for different reasons. In women, it helps stimulate egg production; in men, it can help increase sperm production.
How should Gonal F be stored?
Gonal F should be stored in the refrigerator at 2-8°C. Do not freeze. Keep it out of direct sunlight.
How long does treatment with Gonal F usually last?
The duration of treatment varies depending on the individual's response to the medication and the specific treatment protocol prescribed by the healthcare provider.
Can I use Gonal F during my period?
Treatment typically starts during your menstrual cycle, but the exact timing should be directed by your healthcare provider.
What are the signs of ovarian hyperstimulation syndrome (OHSS)?
Symptoms of OHSS include severe pelvic pain, nausea, vomiting, diarrhea, rapid weight gain, and difficulty breathing. Contact your healthcare provider immediately if these occur.
Can I travel with Gonal F?
Yes, you can travel with Gonal F. Keep it in a cool bag and be mindful of storage temperatures.
Does Gonal F affect mood or cause emotional changes?
Hormonal treatments can affect your mood. Some patients report feeling more emotional during treatment.
Is it safe to drink alcohol while taking Gonal F?
Alcohol can affect fertility and treatment outcomes. It's best to discuss alcohol use with your healthcare provider during treatment.