A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Insulin is a naturally occurring hormone made by the pancreas that helps the body use or store the glucose (sugar) it gets from food. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. As a result, glucose cannot be used or stored properly and accumulates in the bloodstream. Insulin injected under the skin helps to lower blood glucose levels. There are many different types of insulin and they are absorbed at different rates and work for varying periods of time. Regular insulin is a short-acting insulin. It takes 30 to 60 minutes to begin working after injection, and has its maximum effect between 2 and 4 hours after injection. It stops working after 6 to 8 hours. Concentrated regular insulin is used to improve blood glucose control for people with Type 1 or Type 2 diabetes who require more than 200 units of insulin each day.
Your required dose of regular insulin depends on how much natural insulin your pancreas is producing and how well your body is able to use it. Your doctor or diabetes educator will determine the appropriate dose for you according to various lifestyle factors and the blood glucose values obtained while monitoring your blood glucose. Your dose of regular insulin should be injected subcutaneously (under the skin) exactly as instructed by your doctor or diabetes educator. Do not inject concentrated regular insulin into the vein and do not use concentrated regular insulin in insulin infusion pumps. The dose of insulin is measured in international units (IU). Each mL of concentrated regular insulin contains 500 IU. This insulin is injected about 30 minutes before eating a meal. Concentrated regular insulin should be clear and colourless. Do not use the insulin if you notice anything unusual in the appearance of the solution, such as cloudiness, discoloration, or clumping. Concentrated insulin should not be mixed with any other type of insulin. It should not be used in an insulin pump or injected into a vein or muscle. Keep unopened KwikPens in the refrigerator until needed. They may be used until the expiry date on the label. Never allow insulin to freeze. Insulin that is currently in use may be kept at room temperature for no more than 28 days and then discarded. Do not expose insulin to extremely hot temperatures or to sunlight. Keep insulin out of the reach of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Each mL of clear, colourless, aqueous solution, contains 500 units of human biosynthetic insulin (regular insulin). Nonmedicinal ingredients: glycerin, metacresol, zinc oxide and water for injection. Hydrochloric acid and sodium hydroxide are used to adjust pH.
Do not use concentrated regular insulin if you: are allergic to insulin or to any of the ingredients of the medication have low blood glucose (hypoglycemia)
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. redness, itching, or swelling at the site of the injection Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention. Check with your doctor as soon as possible if any of the following side effects occur: signs of low blood glucose: anxiety blurred vision confusion difficulty concentrating difficulty speaking dizziness drowsiness fast heartbeat headache hunger nausea nervousness numbness or tingling of the lips, fingers, or tongue sweating tiredness trembling weakness signs of low potassium levels in the blood (e.g., weakness, fatigue, muscle cramps, irregular heartbeat) symptoms of heart failure (e.g., swelling of the ankles and feet, shortness of breath, sudden weight gain) Stop taking the medication and seek immediate medical attention if any of the following occur: rash or blisters all over body seizures symptoms of a serious allergic reaction (e.g., swelling of the face or throat, difficulty breathing, wheezing, or itchy skin rash) unconsciousness Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.