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Dupixent (Dupilumab)

Prescription requiredOnly Available By Prescription
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Dupixent is an eczema treatment medication available by prescription and given as an injection that provides relief from the red, itchy skin rashes that occur frequently for eczema sufferers. Eczema is also called atopic dermatitis, and Dupilumab is a monoclonal antibody drug that blocks interleukin, a key component in the development of atopic dermatitis and chronic sinusitis. The injections promotes less of the inflammatory response behind eczema on the skin, and in rarer instances Dupixent may be prescribed to treat eosinophilic esophagitis. Buy Dupixent from Canada and get the best lowest Dupixent cost.

What is Eczema?

Eczema is a dermatitis skin condition where inflammation in the skin causes skin rashes and itchy red areas of the skin where the skin may also be dry, cracked, or leathery. The most common affected skin areas are back of knees, wrists, hands and feet but it is also possible to have eczema on the face. In severe cases eczema can affect skin pigments and make areas of skin lighter or darker. Eczema flare ups can last for only a few days, or they may last weeks. The most common type of eczema is atopic dermatitis.

Fact Table
Formula C3000H4672N804O928S18
License FDA approved in 2017
Bioavailability Not applicable (administered via injection)
Legal Status Prescription only
Chemical Name dupilumab
Elimination half-life Approximately 10 to 14 days
Dosage (Strength) 300 mg/mL solution for injection
Pregnancy advice Use only if clearly needed; consult healthcare provider
Brands Dupixent
Protein binding Not applicable
PubChem CID Not available
MedlinePlus number a617034
ChEBI ID Not available
ATC code D11AH05
DrugBank ID DB11941
KEGG ID D10335
Routes of administration Subcutaneous injection

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Directions

Dupixent is administered as a subcutaneous injection under the skin 1x every 2 to 4 weeks based on what is indicated in your prescription

Suitable administration sites are only the upper thigh or abdomen excluding a 2” radius around the navel

Lay syringe on a flat surface and allow it to warm to room temperature for at least 30 minutes before administering injection

Wash and dry hands before beginning. Pinch fold of skin at injection site and insert needle into the skin at a 45 degree angle

Relax pinch and push syringe plunger down to administer the full dose

Lightly press a cotton ball or gauze onto skin at the injection site

Ingredients

The active ingredient in Dupixent is Dupilumab

Cautions

Let your doctor know of any history of asthma, eye or vision problems, or joint pain or if you have any parasitic infections before starting on Dupixent.

Patients using steroidal medications for asthma may not be able to use Dupixent

Patients should not receive live vaccines while using this medication

Syringes should be kept refrigerated before injection but must be allowed to warm up to room temperature before the injection is administered

Dispose of syringes properly and keep out of reach of children

Interactions

Negative drug interactions may occur between Dupixent and other Rx medications, including albuterol, amlodipine, atorvastatin, cetirizine, cyclobenzaprine, doxycycline, famotidine, fluticasone, gabapentin, hydroxyzine, levothyroxine, lisinopril, losartan, meloxicam, metformin, montelukast, omeprazole, pantoprazole, prednisone, rosuvastatin, and trazodone. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Dupixent online.

Side Effects

Dupixent side effects may occur, and some users may experience injection site reactions, sore throat, cold sores, conjunctivitis, sleeping difficulties, joint or tooth pain, gastritis, or facial rash. Asthma sufferers may also experience eosinophilia due to use of this medication. If side effects are experienced, you may want to stop use and meet with a super fat bird again to discuss eczema treatment medication alternatives.


Remember, these are not exhaustive lists, and it's important to consult with a healthcare professional for personalized advice and guidance. If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/MedWatch or call 1-800-FDA-1088


Frequently Asked Questions about Dupixent


Is Dupixent a steroid?

No, Dupixent is not a steroidal medication.


Does Dupixent cause weight gain?

Weight gain is not known to be among potential side effects from using Dupixent, and if you are gaining weight while using Dupixent, it is likely not attributable to the medication.


How long does Dupixent take to work?

Most people using this eczema treatment injections will begin to see noticeable improvements with their skin following the 2nd or 3rd injection with Dupixent. Results may not be as speedy for those with a lower metabolic rate or other contributing factors.


Is Dupixent a biologic?

No, Dupixent is not a biologic medication.


Is Dupixent an immunosuppressant?

No, the active ingredient in Dupixent is Dupilumab, and it is not an immunosuppressant class drug. It is a monoclonal antibody drug.