Also Known as Daxas
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The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Daliresp is a COPD treatment medication used to relieve the breathing difficulties people have with COPD attacks, plus making it so they have fewer of those attacks. It is usually prescribed for people with severe COPD. Daliresp uses may also be to treat bronchitis. Roflumilast is a PDE-4 oral selective phosphodiesterase inhibitor, and it works to limit the inflammation response that causes constriction of the airway. You can buy Daliresp with a prescription here at Canpharm.
Fact Table | |
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Formula | C17H14Cl2F2N2O3 |
License | FDA approved |
Bioavailability | ~80% |
Legal status | Prescription only |
Chemical Name | 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide |
Elimination half-life | 17-30 hours (roflumilast), 27-30 hours (active metabolite roflumilast N-oxide) |
Dosage (Strength) | 250 mcg, 500 mcg |
Pregnancy | Consult Doctor (Pregnancy Category C in the U.S.) |
Brands | Daliresp, Daxas |
Protein binding | 99% |
PubChem CID | 5284373 |
MedlinePlus | a611037 |
ChEBI | 68886 |
ATC code | R03DX07 |
DrugBank | DB01656 |
KEGG | D01896 |
Routes of administration | By mouth |
Standard dosage for Daliresp is to take the medication 1x daily and with or without food. It is best to take it at the same time every day.
The active ingredient in Daliresp is Roflumilast
Let your doctor know of any history of liver disease, cancer, heart disease, tuberculosis, herpes, or immune system disorders like HIV or Lupus before starting on Daliresp
This medication may make you dizzy or drowsy, and it may be advisable to avoid driving or using machinery while taking Daliresp generic
Keep at room temperature and without exposure to light or moisture
Be aware of medication expiry date
Negative drug interactions may occur between Daliresp and other Rx or OTC medications, including albuterol, alprazolam, amlodipine, aspirin, atorvastatin, azithromycin, furosemide, gabapentin, levothyroxine, lisinopril, losartan, metformin, metoprolol, montelukast, guaifenesin, omeprazole, pantoprazole, prednisone, tiotropium, budesonide, formoterol, and tramadol. Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Daliresp online.
Daliresp side effects may occur, and some users may experience diarrhea, stomach or abdominal pain, nausea, headache, dizziness or weight loss. Some people using PDE-4 medications may also find they negatively affect their sleep. If side effect are seen you may want to discontinue use and meet with a doctor again to discuss COPD treatment medication alternatives.
What is Daliresp used for?
Daliresp (roflumilast) is used to reduce the risk of COPD (chronic obstructive pulmonary disease) exacerbations in patients with severe COPD and chronic bronchitis.
How does Daliresp work?
Daliresp works by inhibiting an enzyme called phosphodiesterase-4 (PDE4), which helps reduce inflammation in the airways and lungs.
What happens if you stop taking Daliresp?
Stopping Daliresp may increase the risk of COPD exacerbations and a return of symptoms. Consult your doctor before discontinuing.
How long does it take for Daliresp to start working?
Daliresp may take several weeks to show noticeable improvement in COPD symptoms, though the full effect might be seen after a few months.
Can you just stop taking Daliresp?
It is not recommended to stop taking Daliresp abruptly without consulting your doctor, as it could lead to worsening symptoms.
How to stop taking Daliresp?
To stop taking Daliresp, consult your doctor for a safe discontinuation plan tailored to your health condition.
How long does Daliresp stay in your system?
The half-life of Daliresp is about 17 hours, meaning it may take roughly 3–4 days to be mostly eliminated from your system.
Is Daliresp safe?
Daliresp is generally safe when used as prescribed, but it may not be suitable for people with certain conditions, such as liver disease or depression. Always discuss risks with your doctor.
What are the side effects of Daliresp?
Common side effects include diarrhea, weight loss, nausea, headache, insomnia, and back pain. Rare but serious side effects include mental health changes or allergic reactions.
How long do side effects of Daliresp last?
Side effects may last as long as the medication is in your system. Mild side effects often improve as your body adjusts, while serious side effects should be reported to your doctor immediately.