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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Cabometyx (cabozantinib) is a targeted therapy medication used in the treatment of various types of cancer, including advanced renal cell carcinoma (kidney cancer), hepatocellular carcinoma (liver cancer), and medullary thyroid cancer. It works by inhibiting multiple tyrosine kinases, which are enzymes involved in the growth and spread of cancer cells as well as the development of new blood vessels that tumors need to grow.
Before you buy Cabometyx, it is crucial that you talk to your healthcare provider about potential side effects and Cabometyx cost.
| Fact Table | |
|---|---|
| Formula | Not available |
| License | FDA approved |
| Bioavailability | Not available |
| Legal status | Prescription required |
| Chemical Name | Cabozantinib |
| Elimination half-life | Approximately 55 hours |
| Dosage (Strength) | Varies depending on the condition being treated |
| Pregnancy | Category D - Positive evidence of risk; consult healthcare provider regarding potential benefits and risks |
| Brands | Cabometyx |
| Protein binding | Approximately 99.7% |
| PubChem CID | 2766972 (for Cabozantinib) |
| MedlinePlus | a614045 (for Cabozantinib) |
| ChEBI | 68517 (for Cabozantinib) |
| ATC code | L01XE36 |
| DrugBank | DB08875 (Cabozantinib) |
| KEGG | D10085 (Cabozantinib) |
| Routes of administration | Oral |
Cabometyx should be taken exactly as prescribed by your healthcare provider. The typical dosage involves taking the medication once daily, with or without food. Swallow the tablets whole; do not chew, crush, or open them.
Active Ingredient: Cabozantinib.
Do not use Cabozantinib tablets if you are pregnant, as it can harm the fetus. Effective birth control should be used by both males and females during treatment and for a period after the end of treatment.
Avoid breastfeeding during treatment with Cabometyx and for a few months after the final dose.
Cabometyx may cause dizziness or tiredness; avoid driving or operating heavy machinery until you know how Cabometyx affects you.
Cabometyx can interact with:
Common side effects include:
What is Cabometyx used for?
Cabometyx is used to treat advanced kidney cancer, liver cancer, and thyroid cancer.
How does Cabometyx work?
It works by blocking the activity of enzymes known as tyrosine kinases, which are involved in the growth and spread of cancer cells.
How should I take Cabometyx?
Take Cabometyx as directed by your doctor, usually once daily, with or without food. Do not crush or chew the tablets.
Can I take Cabometyx with other medications?
Some medications can interact with Cabometyx, so it’s important to tell your doctor about all the drugs you are taking, including over-the-counter medications and herbal supplements.
What should I do if I miss a dose of Cabometyx?
If you miss a dose and it's still the same day, take it as soon as you remember. If it's the next day, skip the missed dose and resume your usual dosing schedule.
Can pregnant women take Cabometyx?
Cabometyx should not be used during pregnancy as it can harm the fetus. Effective contraception is recommended for both men and women during treatment.
What are the common side effects of taking Cabometyx?
Common side effects include diarrhea, fatigue, nausea, decreased appetite, and hypertension.
What should I avoid while taking Cabometyx?
Avoid grapefruit and grapefruit juice; avoid driving or operating machinery until you know how Cabometyx affects you.
How long do I need to take Cabometyx?
The duration of treatment with Cabometyx will depend on your response to the medication, the type of cancer being treated, and the advice of your oncologist.
Where can I find more information about Cabometyx?
More information can be found through your healthcare provider or the medication guide provided with the prescription.
