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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Bimzelx is a plaque psoriasis treatment medication used to slow the development of skin plaques for people with this skin disorder, and it may also be prescribed to treat ankylosing spondylitis or psoriatic arthritis. Bimekizumab is an interleukin-17 antagonist drug that blocks the substance from fueling they hyperinflammation response in the skin that is at the root of plaque psoriasis. It is administered as an injection, and you can buy Bimzelx with a prescription here at Canpharm.
| Fact Table | |
|---|---|
| Formula | Monoclonal antibody (protein-based, no standard molecular formula) |
| License | EMA and FDA approved |
| Bioavailability | ~70% (subcutaneous injection) |
| Legal status | Prescription Drug |
| Chemical Name | Bimekizumab (recombinant humanized IgG1 monoclonal antibody targeting IL-17A and IL-17F) |
| Elimination half-life | ~23 days |
| Dosage (Strength) | 160mg solution for injection in pre-filled syringes |
| Pregnancy | Consult Doctor (no sufficient human studies; use only if clearly needed) |
| Brands | Bimzelx |
| Protein binding | Not applicable (monoclonal antibody) |
| PubChem CID | Not available (biological agent) |
| MedlinePlus | Not available |
| ChEBI | Not available |
| ATC code | L04AC21 |
| DrugBank | DB15658 |
| KEGG | D11829 |
| Routes of administration | Subcutaneous injection |
Keep Bimzelx autoinjector in original carton for 30 to 45 minutes to allow it to warm to room temperature
Wash hands with soap and water
Look in viewing window of autoinjector cartridge to see that medication is clear or slightly pearly in color, or it can be colorless to pale brownish-yellow too
Choose from 3 possible injection sites – abdomen (excluding a 2” radius around navel), thigh, or back of upper arm
Clean skin of injection site with an alcohol swab
Remove cap on Bimzelx autoinjector
Hold straight up at 90-degree angle and press down on skin to administer injection
Keep in place for 15 seconds to ensure entire Bimzelx dose is administered. Listen for second click sound to determine that injection is complete and you can pull autoinjector away from the skin
Application with prefilled syringe will differ and proper directions for use will be indicated in your prescription
The active ingredient in Bimzelx is Bimekizumab
Let your doctor know of any history of inflammatory bowel disease, Crohn's disease, ulcerative colitis, tuberculosis, liver dysfunction, or a compromised immune system before starting on Bimzelx injection
Do not administer the injection to the same injection site repeatedly as this will increase the chance of lipodystrophy. It is best to rotate between possible injection sites
This medication may make some live vaccine work less effectively
Using Bimzelx for plaque psoriasis may not be suitable for people with depression or other mental health disorders
Women who are pregnant or breastfeeding should only use this medication if their doctor approves it
Negative drug interactions may occur between Bimzelx and other Rx or OTC medications, including erenumab, amlodipine, bictegravir, emtricitabine, tenofovir alafenamide, celecoxib, cephalexin, clonazepam, secukinumab, duloxetine, emtricitabine, dexlansoprazole, doxycycline, gabapentin, adalimumab, lansoprazole, levothyroxine, pregabalin, metformin, methocarbamol, methotrexate, mirtazapine, mirabegron, ondansetron, apremilast, promethazine, atogepant, upadacitinib, ropinirole, and risankizumab.
Let your doctor know of all medications you are currently taking before getting a prescription and proceeding to buy Bimzelx online.
Bimzelx side effects may occur, and some users may experience acne, cold sores, cough, diarrhea, fungal infections, headache, kidney or bladder infections, muscle or joint pain, rash, stomach flu, folliculitis, or herpes simplex virus. If side effects are seen you may want to discontinue use and meet with a doctor again to discuss plaque psoriasis treatment medication alternatives and a pharmacist for a lower Bimzelx cost.
What is Bimzelx?
Bimzelx (bimekizumab) is a biologic medication that targets and inhibits interleukin-17A and interleukin-17F, which are proteins involved in the inflammatory process.
What is Bimzelx used for?
Bimzelx is used to treat moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Does Bimzelx cause weight gain?
Weight gain is not a commonly reported side effect of Bimzelx. However, individual reactions to biologic medications can vary, so it’s important to monitor any unusual changes in weight and discuss them with your doctor.
How long does it take for Bimzelx to work?
Bimzelx typically starts showing improvement within 2 to 4 weeks after starting treatment, with continued improvements over the following months.
How does Bimzelx work?
Bimzelx works by blocking interleukin-17A and interleukin-17F, which play a significant role in the inflammatory process in psoriasis. By inhibiting these proteins, Bimzelx helps reduce inflammation and plaque formation in the skin.
How to inject Bimzelx?
Bimzelx is administered via subcutaneous injection. It’s usually given once a month after an initial loading phase. The injection should be performed in the fatty tissue under the skin, and your healthcare provider will guide you through the injection process if you’re administering it yourself.
Can Bimzelx be used for other conditions besides psoriasis?
While Bimzelx is currently approved for the treatment of moderate to severe plaque psoriasis, ongoing research is exploring its potential use for other inflammatory conditions, such as psoriatic arthritis.
Are there any long-term risks associated with Bimzelx?
Long-term use of Bimzelx may increase the risk of infections due to its immune-modulating effects. It's important to have regular check-ups and follow your doctor's instructions to monitor for any potential side effects over time.
Can Bimzelx be used with other medications?
Bimzelx may be used with other medications, but it is essential to discuss your full medication list with your doctor to avoid potential interactions or increased risk of side effects.
Can Bimzelx be stopped abruptly?
Bimzelx should not be stopped abruptly without consulting your doctor. If you no longer need the medication or experience side effects, your doctor will guide you on how to taper the treatment safely.
