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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Amjevita (Adalimumab-atto) is an FDA-approved biosimilar to Humira (Adalimumab), designed to treat a variety of chronic inflammatory conditions. As a tumor necrosis factor (TNF) blocker, Amjevita helps reduce inflammation and alleviate symptoms in conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis.
This medication is part of a class known as biologic drugs, which are derived from living cells to target specific parts of the immune system. Amjevita works by blocking the activity of TNF, a substance in the body that causes inflammation and can lead to immune-system related diseases. Before you buy Amjevita, it is crucial that you talk to your healthcare provider about potential side effects and Amjevita cost.
| Fact Table | |
|---|---|
| Formula | C6428H9912N1694O1987S46 |
| License | FDA approved |
| Bioavailability | 64% (subcutaneous injection) |
| Legal status | Prescription Drugs |
| Chemical Name | Adalimumab |
| Elimination half-life | Approximately 2 weeks |
| Dosage (Strength) | 40 mg/0.8 mL or 20 mg/0.4 mL |
| Pregnancy | Category B (use only if clearly needed) |
| Brands | Amjevita |
| Protein binding | 99% |
| PubChem CID | 132775075 |
| MedlinePlus | a603010 |
| ChEBI | 64339 |
| ATC code | L04AB04 |
| DrugBank | DB00051 |
| KEGG | D02857 |
| Routes of administration | Subcutaneous injection |
Amjevita is administered through subcutaneous injection, typically given by a healthcare provider in a clinical setting, although patients can be taught to self-administer the injections at home. It is crucial to follow the Amjevita dosage as prescribed by your healthcare provider.
The active ingredient in Amjevita is Adalimumab-atto.
Amjevita should be used with caution in patients with a history of severe infections or a predisposition to infections, as TNF blockers can impair the ability to fight infections. It is not recommended for use in patients with active tuberculosis or other severe infections until these conditions are fully treated.
All patients should be tested for latent tuberculosis before starting Amjevita.
Patients should be aware of potential allergic reactions. Seek immediate medical attention if symptoms of a serious allergic reaction occur.
Live vaccines should be avoided during treatment with Amjevita.
Amjevita can interact with other medications, which can either increase or decrease its effectiveness or increase side effects. Notable interactions include:
You must disclose all medications you are using to your healthcare provider, including over-the-counter medications, vitamins, and herbal supplements.
While Amjevita can significantly improve inflammatory conditions, it is associated with potential side effects. The most common include:
What is Amjevita?
Amjevita (adalimumab-atto) is a biosimilar to Humira (adalimumab). It is a monoclonal antibody that targets and inhibits tumor necrosis factor-alpha (TNF-a), a substance in the body that causes inflammation.
What is the drug Amjevita used for?
Amjevita is used to treat a variety of inflammatory conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis. It helps reduce inflammation and alleviate symptoms associated with these autoimmune conditions.
How to inject Amjevita?
Amjevita is administered via subcutaneous injection. Here are the general steps for injection:
Is Amjevita an immunosuppressant?
Yes, Amjevita is considered an immunosuppressant because it suppresses the immune system's activity to reduce inflammation and prevent the immune system from attacking healthy tissues.
Can Amjevita cause weight gain?
Weight gain is not a common side effect of Amjevita. However, if you experience significant weight changes, it's important to discuss this with your healthcare provider.
Does Amjevita cause tiredness?
Yes, tiredness or fatigue is a reported side effect of Amjevita. If you experience persistent or severe fatigue, consult your healthcare provider.
How long does Amjevita take to work?
The time it takes for Amjevita to work can vary. Some patients may notice an improvement in their symptoms within 2 to 4 weeks, while others may take longer, potentially up to 12 weeks.
How safe is Amjevita?
Amjevita is considered safe for most patients when used as prescribed. However, it can increase the risk of infections and other side effects. Regular monitoring by a healthcare provider is necessary to ensure safety and effectiveness.
Can you drink alcohol on Amjevita?
There is no specific restriction against drinking alcohol while on Amjevita. However, alcohol can exacerbate certain side effects and may affect your liver. It's best to discuss alcohol consumption with your healthcare provider.
Can I stop Amjevita?
You should not stop taking Amjevita without consulting your healthcare provider. Abruptly discontinuing the medication can lead to a flare-up of your condition. Your healthcare provider can guide you on how to safely discontinue or adjust your treatment if necessary.
