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Only Available By Prescription
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aimovig is a monoclonal antibody that blocks the activation of a certain protein that can produce a migraine attack. This protein, called calcitonin gene- related peptide (CGRP), can cause blood vessels to dilate and cause inflammation and migraine headache pain. Aimovig is a prescription medicine used for the preventive treatment of migraine in adults.
Use Aimovig exactly as directed by your healthcare provider. Follow all directions on your prescription label and read all medication guides or instruction sheets. Aimovig is injected under your skin (subcutaneously) one time each month. A healthcare provider may teach you how to properly use the medication by yourself. If your healthcare provider prescribes the 70 mg dose for you, take one injection. If your healthcare provider prescribes the 140 mg dose for you, take two separate injections one after another, using a different prefilled autoinjector or prefilled syringe for each injection. If you want to use the same body site for the two separate injections, make sure the second injection it is not at the same spot you used for the first injection. Read and carefully follow any Instructions for Use provided with your medicine. Do not use Aimovig if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions. Prepare your Aimovig injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. Each single-use prefilled syringe or autoinjector is for one use only. Throw it away after one use, even if there is still medicine left inside. Do not shake the syringe or autoinjector or you may ruin the medicine. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes. Store Aimovig in its original carton in the refrigerator, away from heat and light. Do not freeze. Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Protect from sunlight. Do not heat the medicine in hot water or in a microwave. You may store the medicine for up to 7 days at room temperature. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets. Usual Adult Dose for Migraine Prophylaxis: 70 mg subcutaneously once a month -Some patients may benefit from 140 mg subcutaneously once a month Comments: -A dose of 140 mg should be administered as 2 consecutive subcutaneous injections of 70 mg each. Use: For the preventative treatment of migraine.
Each 1 mL single-dose prefilled autoinjector and single-dose prefilled glass syringe contains 70 mg erenumab-aooe, acetate (1.5 mg), polysorbate 80 (0.10 mg), and sucrose (73 mg).
You should not use Aimovig if you are allergic to erenumab. Aimovig is not approved for use by anyone younger than 18 years old. Tell your doctor if you have ever had: • an allergy to latex. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether erenumab will harm an unborn baby. However, having migraine headaches during pregnancy may cause complications such as preeclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk Before you inject Aimovig, always check the label of your single-dose prefilled autoinjector or single-dose prefilled syringe to make sure you have the correct medicine and the correct dose. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Get emergency medical help if you have signs of an allergic reaction to Aimovig: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common Aimovig side effects may include: • constipation; or • pain, swelling, or redness where the medicine was injected. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
