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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Afinitor Disperz, containing the active ingredient everolimus, is a specialized medication approved by the FDA to treat specific medical conditions. It belongs to a class of drugs known as mTOR inhibitors, which work by interfering with cellular signaling pathways that promote cell division and growth. Afinitor Disperz is primarily used in treating subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC) in patients who require therapeutic intervention but are not candidates for curative surgical resection. The formulation of this medication allows it to disperse in water, facilitating easier administration, particularly in patients who may have difficulties swallowing tablets.
Before you buy Afinitor Disperz, it is crucial that you talk to your healthcare provider about potential side effects and Afinitor Disperz cost.
| Fact Table | |
|---|---|
| Formula | C53H83NO14 |
| License | FDA approved |
| Bioavailability | Approximately 30% |
| Legal status | Prescription Drugs |
| Chemical Name | Everolimus |
| Elimination half-life | Approximately 30 hours |
| Dosage (Strength) | Available in 2 mg, 3 mg, and 5 mg dispersible tablets |
| Pregnancy | Contraindicated during pregnancy |
| Brands | Afinitor Disperz |
| Protein binding | Approximately 74% bound to serum proteins |
| PubChem CID | 6442177 |
| MedlinePlus | a611016 |
| ChEBI | 40068 |
| ATC code | L01XE10 |
| DrugBank | DB01590 |
| KEGG | D03226 |
| Routes of administration | Oral |
Afinitor Disperz dosage should be taken exactly as prescribed by a healthcare provider. The dosage and length of treatment depend on the patient's condition, response to treatment, and other factors.
The active ingredient in Afinitor Disperz is everolimus.
Patients with a history of hypersensitivity to everolimus or other similar drugs should not use Afinitor Disperz.
Signs of an allergic reaction include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Caution is advised in patients with liver or kidney disease, infections, or a history of certain lung conditions, as everolimus can exacerbate these conditions.
Afinitor Disperz can harm an unborn baby; effective contraception must be used by women of reproductive potential.
It is not recommended for use while breastfeeding due to the potential for adverse effects in the nursing infant.
Everolimus can interact with a wide range of medications, potentially increasing or decreasing its effectiveness or exacerbating side effects. These include CYP3A4 inhibitors and inducers and live vaccines.
While taking Afinitor Disperz, patients may experience various side effects, the severity of which can vary from mild to severe. Common side effects include:
What is Afinitor Disperz used for?
Afinitor Disperz is used to treat certain types of tumors, including:
How does Afinitor work?
Afinitor (everolimus) works by inhibiting the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, proliferation, and survival. By blocking mTOR, Afinitor reduces the growth and spread of cancer cells and decreases the size of tumors.
Is Afinitor a form of chemotherapy?
Afinitor is not classified as traditional chemotherapy. Instead, it is a targeted therapy known as an mTOR inhibitor. Unlike chemotherapy, which attacks rapidly dividing cells indiscriminately, targeted therapies like Afinitor specifically target cancer cells and certain pathways involved in tumor growth.
How long does it take for Afinitor to work?
The time it takes for Afinitor to work can vary depending on the condition being treated and the individual patient. Some patients may see an improvement in their condition within a few weeks, while for others, it might take several months to notice significant changes.
How long do people stay on Afinitor?
The duration of Afinitor treatment depends on the patient's response to the medication and the type of cancer being treated. Some patients may stay on Afinitor for several months to years, as long as the treatment is effective and side effects are manageable.
What foods should you avoid while taking Afinitor?
While taking Afinitor, you should avoid:
Who should not take Afinitor?
People who should not take Afinitor include:
How does the drug Afinitor work?
Afinitor works by inhibiting the mTOR pathway, which plays a crucial role in the regulation of cell growth, proliferation, and survival. By blocking this pathway, Afinitor slows down the growth of cancer cells and reduces tumor size.
Can you drink alcohol with Afinitor?
There is no direct contraindication to drinking alcohol while taking Afinitor. However, alcohol can cause liver damage, and since Afinitor can also affect liver function, it is generally advisable to limit alcohol consumption and discuss with your healthcare provider before drinking alcohol while on Afinitor.
Is Afinitor an immunosuppressant?
Yes, Afinitor has immunosuppressant properties. It can weaken the immune system, which may increase the risk of infections. This is important to consider, especially for patients who are also receiving other treatments that suppress the immune system.
